Devin Phillips

Faculty & School/Dept.

Faculty of Health - School of Kinesiology & Health Science

Degrees

BSc - 2008
University of Nevada, Las Vegas
Las Vegas, Nevada

MSc - 2014
University of Alberta
Edmonton, Alberta

PhD - 2020
University of Alberta
Edmonton, Alberta

Biography

Dr. Devin Phillips is an assistant professor of applied cardiorespiratory physiology in the School of Kinesiology and Health Science at York University. He completed his graduate work in the Faculty of Kinesiology, Sport, and Recreation at the University of Alberta, followed by a postdoctoral fellowship in the Department of Medicine at Queen’s University. 

Selected Publications

# indicates trainee

Berton DC, Plachi F, James MD, Vincent SG, Smyth RM, Domnik NJ, Phillips DB, de-Torres JP, Nery LE, O’Donnell DE, Neder JAS. 2023. Dynamic ventilatory reserve on incremental exercise: Reference values and clinical validation in COPD. Annals Amer Thor Soc. Accepted July 2023

Smyth RM#, James MD, Vincent SG, Milne KM, Marillier M, Domnik NJ, de-Torres JP, Moran-Mendoza O, Phillips DB, O’Donnell DE, Neder JAS. Determinants of exercise intolerance in patients with fibrosing interstitial lung disease and a severely impaired DLCO. Resp Care. Accepted June 2023

Smyth RM#, Neder JA, James MD, Vincent SG, Milne KM, Marillier M, de-Torres JP, Moran-Mendoza O, O’Donnell DE, Phillips DB. 2023. Exertional dyspnoea in patients with fibrosing interstitial lung disease and preserved spirometry: The role of ventilatory inefficiency and inspiratory constraints. Resp Physiol Neurobiol. 312: 104041.

Milne KM, James MD, Smyth RM, Vincent SG, Singh N, D’Arisgny, CL, de-Torres JP, de Wit K, Johri A, Neder JA, O’Donnell DE, Phillips DB. 2023 Neurophysiological mechanisms of exertional dyspnea in post-pulmonary embolism syndrome. J Appl Physiol. 134:667-677.

Phillips DB, James MD, O’Donnell CD, Vincent SG, Webb KA, Neder JA, O’Donnell DE. 2022. Physiological predictors of morbidity and mortality in COPD: The relative importance of low inspiratory capacity and inspiratory muscle weakness. J Appl Physiol. 133:679-688.

• American Physiological Society Select Award for Distinction (October 2022)

James MD#, Phillips DB, Vincent SG, Neder JA, Abdallah S, Donovan A, Smith BM, Jensen D, O’Donnell DE. 2022. Exertional dyspnoea in patients with mild-to-severe Chronic Obstructive Pulmonary Disease (COPD): Neuromechanical mechanisms. J Physiol. 600(18):4227-4245

• Editorial by Jolley CJ. doi.org/10.1113/JP283583.

Neder JAS, Phillips DB, O’Donnell DE, Dempsey JA. 2022. Excess ventilation and exertional dyspnoea in heart failure and pulmonary hypertension. Eur Resp J. E-pub ahead of print.

Neder JAS, Kirby M, Santyr G, Pourafkari M, Smyth R, Phillips DB, Crinion S, de-Torres JP, O’Donnell DE. 2022. Improving ventilation/perfusion mismatching: An unmet need in the pharmacological treatment of COPD. Chest. E-pub ahead of print.

Phillips DB, Elbehairy AF, James MD, Vincent SG, Milne KM, de-Torres JP, Neder JAS, Kirby M, Jensen D, Stickland MK, Guenette JA, Smith BM, Aaron SD, Tan WC, Bourbeau J, O’Donnell DE. 2022. Impaired ventilatory efficiency, dyspnea and exercise intolerance in Chronic Obstructive Pulmonary Disease. Results from the CanCOLD study. Am J Resp Crit Care Med.  205(12):1391-1402.

• Editorial by Calverley P. doi.org/10.1164/rccm.202203-0579ED

Brotto AB, Phillips DB, Meah VL, Ross BA, Fuhr DB, van Diepen S, Stickland MK. 2022. Inhaled nitric oxide does not improve maximal oxygen consumption in endurance trained and untrained healthy individuals. Eur J Appl Physiol. 122(3):703-715.

Phillips DB, Neder JA, Elbehairy AF, Milne KM, James MD, Day AG, de Torres JP, Webb KA, O’Donnell DE. 2021. Qualitative components of dyspnea during incremental exercise across the COPD continuum. Med Sci Sport Exer. 53:2467-2476.

James MD#, Phillips DB, Elbehairy AF, Milne KM, Vincent SG, Domnik NJ, de Torres JP, Neder JA, O’Donnell DE. 2021. Mechanisms of exertional dyspnea in patients with mild COPD and a low resting DLCO. J COPD. 18:501-510.

Phillips DB, James MD, Elbehairy AF, Milne KM, Vincent SG, Domnik NJ, de Torres JP, Neder JA, O’Donnell DE. 2021. Dyspnea and exercise intolerance in patients with mild COPD: The role of reduced ventilatory efficiency and diffusing capacity for carbon monoxide. Respirology. 26:786-795.

• Editorial by Thompson BR. doi.org/10.1111/resp.14112

Phillips DB, Brotto AB, Ross BA, Bryan TL, Wong EYL, Meah VL, Fuhr DB, van Diepen S, Stickland MK. 2021. Inhaled nitric oxide improves ventilatory efficiency and exercise capacity in patients with mild chronic obstructive pulmonary disease: a randomized-control crossover trial. J Physiol. 599:1665-1683.

Phillips DB, Domnik NJ, Elbehairy AF, Preston ME, Milne KM, James MD, Vincent SG, Ibrahim-Masthan M, Neder JA, O’Donnell DE. 2021. Elevated exercise ventilation in mild COPD is not linked to enhanced central chemosensitivity. Resp Physiol Neurobiol. 284:103571.

Neder JA, Berton DC, Phillips DB, O’Donnell DE. 2021. Exertional ventilation-CO2 output relationship in COPD: from physiological mechanisms to clinical applications. Eur Resp Rev. 30: 200190.

Collins SÉ, Phillips DB, Brotto AB, Rampuri Z, Stickland MK. 2021. Ventilatory efficiency in athletes, asthma, and obesity. Eur Resp Rev. 30:200206.

Domnik NJ, James MD, Scheeran R, Ayoo G, Taylor S, Di Luch A, Milne KM, Vincent, S, Phillips DB, Elbehairy AF, Crinion S, Driver H, Neder JA, O’Donnell DE. 2021. Deterioration of nighttime respiratory mechanics in chronic obstructive pulmonary disease: Impact of bronchodilator therapy. Chest. 159(1): 116-127

Milne KM, Domnik NJ, Phillips DB, James MD, Neder AJ, O’Donnell DE. 2020. Non-invasive evaluation of dynamic respiratory mechanics during CPET. Frontiers Med. 7:548.

Milne KM, Ibrahim-Masthan M, Scheeran R, James MD, Phillips DP, Moran-Mendoza O, Neder JA, O’Donnell DE. 2020. Increased inspiratory neural drive and exertional dyspnea in mild to moderate interstitial lung disease: Effect of inhaled fentanyl. Resp Physiol Neurobiol. 282:103511.

James MD#, Milne KM, Phillips DB, Elbehairy AF, Neder JA, O’Donnell DE. 2020. Dyspnea and exercise limitation in mild COPD: the value of CPET. Frontiers Med. 7:442.

Phillips DB, Collins SÉ, Stickland MK. 2020. Measurement and interpretation of exercise ventilatory efficiency. Frontiers Physiol. 11:659.

Ross BA, Brotto AR, Fuhr DP, Phillips DB, van Diepen S, Bryan TL, Stickland MK. 2020. The supine position improves but does not normalize the blunted pulmonary capillary blood volume response to exercise in mild COPD. J Appl Physiol. 128:925-933.

Collins SÉ, Phillips DB, McMurtry MS, Bryan TL, Paterson DI, Wong EYL, Ezekowitz JA, Forhan MA, Stickland MK. 2020. The effect of carotid chemoreceptor inhibition on exercise tolerance in chronic heart failure. Front Physiol. 11:00195.

Phillips DB, Collins SÉ, Bryan TL, Wong EYL, McMurtry MS, Bhutani M, Stickland MK. 2019. The effect of carotid chemoreceptor inhibition on exercise tolerance in chronic obstructive pulmonary disease: a randomized-controlled crossover trial. Resp Med. 160: 105815.

Phillips DB, Ehnes CM, Stickland MK, Petersen SR. 2019. Ventilatory responses in males and females during graded exercise with and without thoracic load carriage. Eur J Appl Physiol. 119: 441-453.

Tedjasaputra V, van Diepen S, Phillips DB, Wong EYL, Bhutani M, Michaelchuk WW, Bryan TL, Stickland MK. 2018. Pulmonary capillary blood volume response to exercise is diminished in mild chronic obstructive pulmonary disease. Resp Med. 145:57-65.

Moore LE, Brotto AR, Phillips DB, Bhutani M, Stickland MK. 2018. Exertional dyspnea and operating lung volumes in asthma. J Appl Physiol. 125:870-877.

Phillips DB, Steinback CD, Collins SÉ, Fuhr DP, Bryan TL, Wong EYL, Tedjasaputra V, Bhutani M, Stickland MK. 2018. The carotid chemoreceptor contributes to the elevated arterial stiffness and vasoconstrictor outflow in COPD. J Physiol. 15:3233-3244.

• Article was highlighted in a special edition release “Advances in cellular and integrative control of oxygen and carbon dioxide homeostasis”


• Journal club articles by Brock JM doi/10.1113/JP276597 and Oliveira DM et al doi/10.1113/JP276986

Phillips DB, Stickland MK, Petersen SR. 2016. Physiological and performance consequences of heavy thoracic load carriage in females. Appl Physiol Nutr Metab. 41:741-748.

Phillips DB, Stickland MK, Lesser IA, Petersen SR. 2016. The effects of heavy load carriage on physiological responses to graded exercise. Eur J Appl Physiol. 116:19-27.

Other Research Outputs

Textbook chapter

Dempsey JA, Neder JAS, Phillips DB, O’Donnell DE. 2022. The physiology and pathophysiology of exercise hyperpnea. Invited submission to Handbook Clin Neurology. 188:201-232.

Affiliations

Canadian Society for Exercise Physiology
Certified Clinical Exercise Physiologist (CEP)

Queen's University
Adjunct Professor - Department of Medicine

Awards

American Physiological Society Select Award for Distinction - 2022

Supervision

Currently available to supervise graduate students: Yes

Currently taking on work-study students, Graduate Assistants or Volunteers: Yes

Available to supervise undergraduate thesis projects: Yes

Current Research

Dr. Phillips’ research program focuses on healthy aging and biological sex-differences, and their interrelationships with cardiorespiratory and neuromechanical function, perceived breathlessness, and exercise performance. Additionally, his research evaluates the feasibility and efficacy of novel treatments that can be used in conjunction with exercise training to reduce breathlessness and improve physiological function, exercise performance, and quality of life, in adults living with cardiorespiratory disease.

Research Projects

Understanding sex differences in the control of breathing
Role: Principal Investigator
Year Funded: 2023
Funded by: York University

Curriculum Vitae (C.V. file):

CV of Devin Phillips